The Rollins chemistry department sponsors seminar speakers and special events throughout the year.
September 30 (Tuesday): Dr. Katherine Franz, Duke University, will present "Of Metals and Microbes...a Tale of Coordination Chemistry"
Time: 4:00 pm
Location: Bush 308, Rollins College
Description: Metal ions are required nutrients for many organisms but also potent toxins if misappropriated. The distribution networks of inorganic elements are therefore strategic battlegrounds in the fight between hosts and pathogens. Disrupting a supply chain to starve microbial pathogens of a required element is one strategy. On the other hand, overburdening an invading microorganism’s capacity to regulate metals can intensify pathogen killing. The opportunity to pharmacologically manipulate metal distribution along this host/pathogen interface represents an opportunity to create innovative broad-spectrum antimicrobial agents. In this talk I will present our lab’s progress on developing small molecules that mobilize metal ions in response to infection in order to boost immune cells’ microbiocidal activity while evading metal-resistance mechanisms of the pathogen.
Talk is free and open to the public.
October/November: Additional seminars TBA